With several servicemen in town for the Holiday, the USO is asking residents to invite a serviceman for Thanksgiving Dinner. Leroy and Marjorie talk Gildy into inviting several of them, but when he finally goes to invite them, they've already been invited by others.
Jack invites the gang for Thanksgiving Dinner, and has Dennis in black face to help Rochester serve. Phil Harris sings "Chattanooga Choo Choo," on one of Jack's records. Rochester's having trouble cooking the duck they're having. Phil arrives with his wife Alice Faye who sings "Tropical Magic" after dinner.
A dramatization of the Office of Naval Intelligence's mission into Nazi occupied territory in an effort to smuggle professor Niels Bohr and his bottle of Heavy Water, the last of the substance in all of Europe, out of Denmark and safely back to the United States.
Don Ameche welcomes Edgar Bergen and Charlie McCarthy on their first appearance on the program. Edgar needs to hire a butler, and Charlie wants the job so Edgar instructs him. Dorothy Lamour sings "What Will I Tell My Heart." Don and Ann Harding perform a scene from, "The Guardsman." W. C. Fields meets Edgar and Charlie, then Don asks Fields about his illness. Don sings "Never In A Million Years." Don interviews Rodgers and Hart.
Miss Brooks is at first glad that her rival for Mr Boynton's affections, Miss Enright, must leave school for the semester, until she learns she will be forced to take over teaching Miss Enright's First Aid course.
A professor has a plan to murder his nephew by hypnosis to get his inheritance, but the nephew meets Lamont and Margo who become suspicious of the boy's behavior, prompting an investigation by The Shadow.
Groucho Marx insists Bill Goodwin announce him, and isn't satisfied with it. Judy Garland sings, "I Never Knew." Jose Iturbi performs a classical number, but Judy wants him to 'make with the jive,' and teaches him to swing. Groucho introduces Betty Grable his "mom", and she goes along with the gag. Betty gets love advice from Groucho.
Fibber receives the results of a handwriting analysis he sent for through the mail, that claims he has "the common touch" and should be physician. Believing the analysis is accurate, Fibber immediately begins diagnosing everyone who stops by.