Host Graham McNamee introduces Harry Von Zell who describes what is meant by "warming up the audience." What a Pot Of Gold winner did with his prize money. How a radio program influenced a listener. The story behind animals on radio programs. Oddities in radio. The radio editor of The New York Sun answers questions from listeners. A spy story told by Captain Tim Healy.
Eddie sings "Swanee" to start the show. "Around The Clock With Eddie Cantor," follows Eddie throughout his day, starting with no breakfast, then he goes to the studio to listen to Nora Martin sing "A Little on the Lonely Side," and then tracks down his missing writers, Harry Von Zell's little son tells Eddie his troubles, then Eddie introduces The Mad Russian to Hoagy Carmichael who sings "Billiaduk."
Henry invites Kathleen to dinner, but he also invites Homer and then finds out she doesn't like Homer. Henry's mother gives Kathleen advice on how to handle Homer, and Henry's father tells him how to deal with Kathleen, then the trouble starts.
A reporter interviews a test pilot that will operate a rocket sled. How the average American husband handles a leaky faucet. An interview with a man starting his own labor union. Stan tries to sing the song "Sh-Boom," from his latest album.
Jerry Colonna telephones Bob from jail for speeding. Skinnay Ennis sings "In The Middle Of May," then Frances Langford sings "It's Been A Long, Long Time." Joe E. Brown and Bob perform an old vaudeville routine.
A couple driving in heavy fog in the middle of the night hear a scream and the wife jumps out to investigate, and disappears into the fog. The husband searches frantically from house to house and falling to find her, seeks the aide of Gregory Hood and they eventually find her unconscious, near a murdered man.